Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760688 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠We hypothesize that multiple zyxin LIM domains may enhance force sensitivity. ⺠We analyze the accumulation of tandem dimer or trimer LIM domain and traction force. ⺠Tandem LIM variants reduces VASP accumulation at focal adhesions. ⺠Force sensitivities are similar among single and tandem LIM variants. ⺠Single LIM domain of zyxin has the optimal force sensitivity.
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Authors
Amanda N. Steele, Grant M. Sumida, Soichiro Yamada,