Article ID Journal Published Year Pages File Type
10760688 Biochemical and Biophysical Research Communications 2012 5 Pages PDF
Abstract
► We hypothesize that multiple zyxin LIM domains may enhance force sensitivity. ► We analyze the accumulation of tandem dimer or trimer LIM domain and traction force. ► Tandem LIM variants reduces VASP accumulation at focal adhesions. ► Force sensitivities are similar among single and tandem LIM variants. ► Single LIM domain of zyxin has the optimal force sensitivity.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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