Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760700 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠β-Catenin expression were markedly down-regulated by CTNNB1 shRNA. ⺠CTNNB1 shRNA could inhibit the proliferation of RPMI8226 cells. ⺠Significantly profound apoptotic cell death in CTNNB1 shRNA cells. ⺠In vivo, CTNNB1 silence led to a growth inhibition of myeloma growth. ⺠c-myc and β-catenin in the expression cells of cleaved caspase-3 were increased.
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Authors
Wenqing Liang, Chengwei Yang, Yu Qian, Qiang Fu,