| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760730 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠IFI16 can form protein-DNA complexes with supercoiled DNA. ⺠IFI16 protein binds strongly to negatively superhelical plasmid DNA at a native superhelical density. ⺠IFI16 strongly prefers binding to cruciform DNA over linear duplex DNA. ⺠Electrophoretic retardation assay is suitable for determining IFI16-DNA complexes.
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Authors
Václav Brázda, Jan Coufal, Jack C.C. Liao, Cheryl H. Arrowsmith,