Article ID Journal Published Year Pages File Type
10760737 Biochemical and Biophysical Research Communications 2012 6 Pages PDF
Abstract
► Sodium arsenite down-regulates the protein expression level of XIAP in HCC. ► Sodium arsenite inhibits the de novo XIAP synthesis and its IRES activity. ► Sodium arsenite decreases XIAP stability and promotes its proteasomal degradation. ► Overexpression of XIAP attenuates the pro-apoptotic effect of sodium arsenite.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Sodium arsenite down-regulates the expression of X-linked inhibitor of apoptosis protein via translational and post-translational mechanisms in hepatocellular carcinoma
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