Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760815 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠High levels of glucocorticoids cause muscle wasting and weakness. ⺠Dexamethasone-induced myotube atrophy was attenuated by HMB. ⺠p38/MAPK and PI3K/Akt signaling are involved in the effects of HMB. ⺠Patients with glucocorticoid-induced muscle wasting may benefit from treatment with HMB.
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Authors
Zaira Aversa, Nima Alamdari, Estibaliz Castillero, Maurizio Muscaritoli, Filippo Rossi Fanelli, Per-Olof Hasselgren,