Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760827 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠FGF7 strongly and rapidly down-regulates the expression of CYP7A1 in hepatocytes. ⺠FGF7 suppresses the expression of CYP7A1 via FGFR2 and downstream JNK activation. ⺠Blocking FGF7 abrogates HSC-induced inhibition of CYP7A1 expression in hepatocytes.
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Biochemistry
Authors
Zhichao Sun, Xuemei Yu, Weibin Wu, Dongwei Jia, Yinle Chen, Lingling Ji, Xijun Liu, Xiaomin Peng, Yintao Li, Lili Yang, Yuanyuan Ruan, Jianxin Gu, Shifang Ren, Songwen Zhang,