| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760850 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠The Cact gene is induced in mouse skeletal muscle after 24 h of fasting. ⺠The Cact gene contains a functional consensus sequence for ERR. ⺠This sequence binds ERRα both in vivo and in vitro. ⺠This ERRE is required for the activation of Cact expression by the PGC-1/ERR axis. ⺠Our results add Cact as a genuine gene target of these transcriptional regulators.
Keywords
CPTPGC-1cACTERRPPARPPREFatty acid oxidationchromatin immunoprecipitationMuscleperoxisome proliferator-activated receptor response elementMetabolismperoxisome proliferator-activated receptor gamma coactivator 1CHiPCarnitine palmitoyltransferasecarnitine/acylcarnitine translocaseperoxisome proliferator-activated receptorestrogen-related receptorthyroid hormone receptor
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Authors
Mar Gacias, Albert Pérez-MartÃ, Magdalena Pujol-Vidal, Pedro F. Marrero, Diego Haro, Joana Relat,