| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760859 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠eIF4E is associated with the formation and progression for breast cancer. ⺠pSecX-t4EBP1 can downregulated the expression of eIF4E in direct binding. ⺠We transfected pSecX-t4EBP1 into a mouse xenograft model. ⺠It can significantly inhibit tumor growth and enhance the radiosensitivity. ⺠The possible mechanism is downregulation of HIF-1α expression.
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Authors
Hua Yang, Li-Wen Li, Mei Shi, Jian-Hua Wang, Feng Xiao, Bin Zhou, Li-Qiong Diao, Xiao-Li Long, Xiao-Li Liu, Lin Xu,