Article ID Journal Published Year Pages File Type
10760864 Biochemical and Biophysical Research Communications 2012 6 Pages PDF
Abstract
► RA induces limb hairy2 expression. ► RA promotes a short-term, transient increase of p-Erk and p-Akt in the anterior limb. ► RA enhances Gli3-A/Gli3-R in the anterior limb, in a short-term, transient manner. ► BMP4 inhibits hairy2 expression in the distal limb. ► RA shapes limb hairy2 expression pattern during limb development.
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Retinoic acid signaling regulates embryonic clock hairy2 gene expression in the developing chick limb
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