Article ID Journal Published Year Pages File Type
10760867 Biochemical and Biophysical Research Communications 2012 5 Pages PDF
Abstract
► CITED2 mutant decreased its ability to mediate the expression of VEGF and PITX2C. ► CITED2 mutant disrupt its competitiveness with HIF-1α for binding to CBP/p300. ► CITED2 mutant decreased cooperation between CITED2 and TFAP2C.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
CITED2 mutation links congenital heart defects to dysregulation of the cardiac gene VEGF and PITX2C expression
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