Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760876 | Biochemical and Biophysical Research Communications | 2012 | 7 Pages |
Abstract
⺠Chloroquine synergistically killed LNCaP cells during androgen deprivation treatment. ⺠Chloroquine inhibited the function of autolysosomes and decreases the cytosolic ATP. ⺠Chloroquine induced nuclear and DNA fragmentation in androgen deprived LNCaP. ⺠Chloroquine may be an useful adjuvant in hormone ablation therapy in PCa patients.
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Authors
Ramesh R. Kaini, Chien-An A. Hu,