| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760878 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠HOCl and N-chloramines target specific cellular thiol proteins. ⺠Protein folding enzymes and galectin-1 are particularly susceptible to oxidation. ⺠N-chloramines formed on histamine may propagate inflammatory damage.
Keywords
HOClRuBPSN-ChloramineTNBIAFHBSSDTNBHCAECGAPDHTCADTT5-Iodoacetamidofluorescein5,5′-dithio-bis(2-nitrobenzoic acid)MPOMTT5-thio-2-nitrobenzoic acidtrichloroacetic acidhypochlorous acidProtein oxidationThioldithiothreitolhuman coronary artery endothelial cellsEndothelial cellHank’s buffered salt solutionmyeloperoxidaseglyceraldehyde-3-phosphate dehydrogenase
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Fiona A. Summers, Anna Forsman Quigley, Clare L. Hawkins,