Article ID Journal Published Year Pages File Type
10760899 Biochemical and Biophysical Research Communications 2012 7 Pages PDF
Abstract
► Compound 48/80-mediated local mast cell degranulation causes pain and edema in mice. ► Pain responses are mediated by neutrophil influx and histamine signaling. ► Mast cell deficient mice lack pain responses to compound 48/80. ► Plantar mast cell reconstitution restores these thermal and mechanical pain responses.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , , , , , , , ,