Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760912 | Biochemical and Biophysical Research Communications | 2012 | 7 Pages |
Abstract
⺠Polycomb protein-regulated loci are modified epigenetically in liver cancer cells. ⺠Non-polycomb tumor suppressors are modified epigenetically in liver cancer cells. ⺠Polycomb targets become hypomethylated in early-stage liver cancer. ⺠A non-polycomb tumor suppressor gene is hypermethylated in early-stage liver cancer. ⺠The observed changes in DNA methylation status occur independently in liver cancer.
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Authors
Yao-Li Chen, Chih-Jan Ko, Ping-Yi Lin, Wan-Ling Chuang, Chia-Chen Hsu, Pei-Yi Chu, Mei-Yu Pai, Chun-Chun Chang, Ming-Han Kuo, Yi-Ru Chu, Chun-Hsin Tung, Tim H.-M. Huang, Yu-Wei Leu, Shu-Huei Hsiao,