Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760916 | Biochemical and Biophysical Research Communications | 2012 | 7 Pages |
Abstract
⺠False-positive gene-trap events were frequently observed with the retroviral vector. ⺠Most of the retroviral integration sites were found in the 5Ⲡuntranslated region. ⺠The lentiviral vector integrated uniformly throughout transcriptional units. ⺠Lentiviral vectors can trap active genes more efficiently than retroviral vectors.
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Authors
Tomoyuki Yamaguchi, Azusa Morikawa, Hiroyuki Miyoshi,