Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10760934 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠BDNF protected HT-29 colorectal cancer cells from the antitumor effect of cetuximab. ⺠TrkB inhibition potentiated the antitumor effect of cetuximab. ⺠BDNF/TrkB signaling might be involved in resistance to anti-EGFR therapy.
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Authors
Caroline Brunetto de Farias, Tiago Elias Heinen, Rafael Pereira dos Santos, Ana Lucia Abujamra, Gilberto Schwartsmann, Rafael Roesler,