| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10760959 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Pyroptosis is induced through the inhibition of a tyrosine phosphatase by sodium orthovanadate. ⺠Phosphatase inhibition induces ASC speck formation and secretion of IL-1β. ⺠Phosphorylation is important in the activation of caspase-1 and induction of pyroptosis.
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Authors
Mohammed G. Ghonime, Obada R. Shamaa, Ramadan A. Eldomany, Mikhail A. Gavrilin, Mark D. Wewers,