Article ID Journal Published Year Pages File Type
10760999 Biochemical and Biophysical Research Communications 2012 7 Pages PDF
Abstract
► It is known that stem cells can be enriched in a non-adherent sphere culture. ► We compared stem cell-related genes between 4T1 cells and 4T1-derived spheres. ► Wnt1 was significantly up-regulated in the 4T1-derived spheres. ► Wnt1 regulates stem-cell like properties.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Inhibition of Wnt1 expression reduces the enrichment of cancer stem cells in a mouse model of breast cancer
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