| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761036 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠Mammalian target of rapamycin (mTOR) up-regulates excitatory amino acid transporter EAAT3. ⺠The effect is reversed by rapamycin. ⺠mTOR coexpression increases EAAT3 protein abundance in the cell membrane. ⺠mTOR presumably increases carrier protein insertion into the cell membrane. ⺠The effect of mTOR may impact of neuroexcitotoxicity and regulation of autophagy.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Ahmad Almilaji, Tatsiana Pakladok, Anne Guo, Carlos Munoz, Michael Föller, Florian Lang,