| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761146 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠HBx inhibits p53-mediated upregulation of Mfn2 in HCC. ⺠Doxorubicin cannot upregulate Mfn2 protein expression in HepG2.2.15. ⺠P53-mediated upregulation of Mfn2 can be blocked by HBx. ⺠HBx counteracts Mfn2 promoter activity in doxorubicin-treated HepG2 cells. ⺠HBx inhibits the interactions between p53 and the p53 binding site of Mfn2.
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Authors
Weilin Wang, Dongkai Zhou, Jianfeng Wei, Zehui Wu, Xiaofei Cheng, Qiang Sun, Haiyang Xie, Lin Zhou, Shusen Zheng,