Article ID Journal Published Year Pages File Type
10761179 Biochemical and Biophysical Research Communications 2012 7 Pages PDF
Abstract
► Serial qPCR accurately determines fragmentation state of any given DNA sample. ► Serial qPCR demonstrates different preservation of the nuclear and mitochondrial genome. ► Serial qPCR provides a diagnostic tool to validate the integrity of bioptic material. ► Serial qPCR excludes degradation-induced erroneous quantification.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
qPCR-based mitochondrial DNA quantification: Influence of template DNA fragmentation on accuracy
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