Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761184 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Successful use of a novel RNA-specific bioinformatic tool, RNA SCOPE. ⺠Identified novel 3ⲠUTR cis-acting element that destabilizes a reporter mRNA. ⺠Show exosome subunits are required for cis-acting element-mediated mRNA instability. ⺠Define precise sequence requirements of novel cis-acting element. ⺠Show that microarray-defined exosome subunit-regulated mRNAs have novel element.
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Authors
Daniel L. Kiss, Dezhi Hou, Robert H. Gross, Erik D. Andrulis,