Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761189 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Sorafenib treatment upregulated GSK-3β levels in RCC cells. ⺠Pharmacologic inhibition of GSK-3 suppressed xenograft RCC tumor growth. ⺠Inhibition of GSK-3 enhanced antitumor effect of sorafenib in vitro and in vivo.
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Authors
Hisashi Kawazoe, Vladimir N. Bilim, Andrey V. Ugolkov, Kaori Yuuki, Sei Naito, Akira Nagaoka, Tomoyuki Kato, Yoshihiko Tomita,