Article ID Journal Published Year Pages File Type
10761193 Biochemical and Biophysical Research Communications 2012 5 Pages PDF
Abstract
► We reconstructed (eIF5-CTD)-(eIF2β-NTD) and (eIF2Bε-CTD)-(eIF2β-NTD) in vitro. ► We examined structural changes of eIF2β-NTD, eIF5-CTD and eIF2Bε-CTD. ► We found that eIF2β-NTD works as an intrinsically disordered domain. ► We propose the binding mechanism of eIF2β-NTD with eIF5-CTD and eIF2Bε-CTD.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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