| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761201 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠GFP reporter stable cell lines that recapitulate exon 7 inclusion of SMN1 and SMN2 pre-mRNA are established. ⺠Alternative splicing of SMN1-GFP and SMN2-GFP mini-gene is similar to endogenous pre-mRNA splicing of SMN1 and SMN2 gene. ⺠SMN1-GFP stable cell line expresses â¼fourfold GFP protein than SMN2-GFP stable cell line does. ⺠shRNA knockdown of hnRNP A1 in SMN2-GFP stable cell line promotes exon 7 inclusion of SMN2-GFP minigene.
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Authors
Sunghee Cho, Heegyum Moon, Xiaoming Yang, Jianhua Zhou, Hye-Ran Kim, Myung-Geun Shin, Tiing Jen Loh, Xuexiu Zheng, Haihong Shen,