Article ID Journal Published Year Pages File Type
10761207 Biochemical and Biophysical Research Communications 2012 4 Pages PDF
Abstract
► CFTR mutations produce cystic fibrosis. ► Chloride transport depends on the regulatory domain phosphorylation. ► Regulatory domain is intrinsically disordered. ► Secondary structure and protein stability change upon phosphorylation.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Thermodynamic study of the native and phosphorylated regulatory domain of the CFTR
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