| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761217 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Leucine-rich repeat (LRR) domain of a bacterial protein activates TLR2. ⺠Peptide repeats in the LRR domain responsible for TLR2 activation were identified. ⺠A common peptide motif in these repeats interacts with TLR2. ⺠This peptide motif in a TLR2-dependent manner activates macrophages. ⺠This study identifies a novel non-acylated peptide ligand of TLR2.
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Authors
Srinivas R. Myneni, Rajendra P. Settem, Hakimuddin T. Sojar, James P. Malone, Vuokko Loimaranta, Takuma Nakajima, Ashu Sharma,