| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761250 | Biochemical and Biophysical Research Communications | 2012 | 7 Pages |
Abstract
⺠MLL-AF9 directly induces the expression of DACH. ⺠DACH1 enhances the colony-forming capacity and blocks the differentiation of myeloid cells. ⺠DACH1 acts as a coactivator with HOXA9. ⺠DACH1 could be down-regulated by C/EBPα and GATA-1 during myeloid differentiation. ⺠Novel mechanism of myeloid leukemogenesis mediated by DACH1.
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Authors
Jae-Woong Lee, Hyeng-Soo Kim, Junmo Hwang, Young Hun Kim, Ga Young Lim, Wern-Joo Sohn, Suk-Ran Yoon, Jae-Young Kim, Tae Sung Park, Seung Hwan Oh, Kwon Moo Park, Sang Un Choi, Zae Young Ryoo, Sanggyu Lee,