| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761251 | Biochemical and Biophysical Research Communications | 2012 | 4 Pages |
Abstract
⺠Hypermethylation of gene promoters is linked to carcinogenesis. ⺠Wilm's tumor (WT1) gene is involved in K Ras signaling and lung cancer cell growth. ⺠Methylation of 29 CpG islands in WT1 5Ⲡregion was assessed in 16 NSCLC pts. ⺠WT1 gene methylation is significantly increased in NSCLC.
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Authors
Pierdonato Bruno, Giovanna Gentile, Rita Mancini, Claudia De Vitis, Maria Cristina Esposito, Davide Scozzi, Mario Mastrangelo, Alberto Ricci, Ibrahim Mohsen, Gennaro Ciliberto, Maurizio Simmaco, Salvatore Mariotta,