| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761282 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠A Src-PDGFRA-Raf-Mapk axis mediates TKI resistance in rhabdomyosarcoma (RMS). ⺠Combined inhibition of Pdgfra and Src had additive effect on resistant cell viability. ⺠Sorafenib halted progression of mouse alveolar rhabdomyosarcoma tumors in vivo.
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Authors
Jinu Abraham, Ying Xuan Chua, Jason M. Glover, Jeffrey W. Tyner, Marc M. Loriaux, Aoife Kilcoyne, Francis J. Giles, Laura D. Nelon, Jennifer S. Carew, Yongjian Ouyang, Joel E. Michalek, Ranadip Pal, Brian J. Druker, Brian P. Rubin, Charles Keller,