Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761283 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠ANG-(1-7) in vitro ameliorates ANG II-induced insulin resistance in rat skeletal muscle. ⺠This beneficial effect of ANG-(1-7) is associated with enhanced Akt Ser473 phosphorylation. ⺠The beneficial effects of ANG-(1-7) can be prevented by the Mas receptor antagonist A779. ⺠The results support targeting the renin-angiotensin system in insulin-resistant muscle.
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Authors
Mujalin Prasannarong, Fernando R. Santos, Erik J. Henriksen,