Article ID Journal Published Year Pages File Type
10761295 Biochemical and Biophysical Research Communications 2012 6 Pages PDF
Abstract
► Lubiprostone chloride transport was examined in Xenopus oocytes. ► We studied ClC-2 and CFTR chloride channels. ► We examined both channels co-expressed with prostaglandin receptor sub-type 4. ► We demonstrate CFTR but not ClC-2 activation by lubiprostone in oocytes.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Lubiprostone activates CFTR, but not ClC-2, via the prostaglandin receptor (EP4)
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