| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761324 | Biochemical and Biophysical Research Communications | 2012 | 7 Pages |
Abstract
⺠Estrogen signaling and demethylation can both control gene expression in breast cancers. ⺠Cross-talk between these mechanisms is investigated in human MCF-7 breast cancer cells. ⺠137 genes are influenced by both 17β-estradiol and demethylating agent 5-aza-2â²-deoxycytidine. ⺠A set of genes is identified as targets of both estrogen signaling and demethylation. ⺠There is no direct molecular interplay of mediators of estrogen and epigenetic signaling.
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Authors
Milica Putnik, Chunyan Zhao, Jan-Ã
ke Gustafsson, Karin Dahlman-Wright,