Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761348 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠hESCs and their progeny, NSCs and neurons, were exposed to ionizing radiation. ⺠Upon irradiation, most hESCs died within 5-7 h. ⺠Surviving NSCs underwent senescence and displayed features of astrocytes. ⺠Surviving NSCs did not display the secretory phenotype expressed by pure astrocytes. ⺠This study is to better understand the stress-responses of hESCs and their progeny.
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Authors
Ying Zou, Ningzhe Zhang, Lisa M. Ellerby, Albert R. Davalos, Xianmin Zeng, Judith Campisi, Pierre-Yves Desprez,