Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761349 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Ox-LDL degrades HSPG, and induces apoptosis and autophagy in endothelial cells. ⺠Heparinase III degrades HSPG, and induces modest apoptosis and autophagy. ⺠Effects of ox-LDL are LOX-1 dependent, but the effects of heparinase II are LOX-1-independent. ⺠Heparinase III enhances the atherogenic phenotype of endothelial cells in response to ox-LDL.
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Authors
Zufeng Ding, Xianwei Wang, Magomed Khaidakov, Shijie Liu, Yao Dai, Jawahar L. Mehta,