Article ID Journal Published Year Pages File Type
10761349 Biochemical and Biophysical Research Communications 2012 6 Pages PDF
Abstract
► Ox-LDL degrades HSPG, and induces apoptosis and autophagy in endothelial cells. ► Heparinase III degrades HSPG, and induces modest apoptosis and autophagy. ► Effects of ox-LDL are LOX-1 dependent, but the effects of heparinase II are LOX-1-independent. ► Heparinase III enhances the atherogenic phenotype of endothelial cells in response to ox-LDL.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , , , , ,