Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761356 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠IL-33 is considered a new therapeutic target for reducing inflammation in asthma. ⺠This study shows that IL-33 is a potent chemoattractant for fibrocytes in asthma. ⺠IL-33 also promotes fibrocyte proliferation without reducing collagen production. ⺠The study uncovers a novel non-inflammatory, profibrotic function of IL-33.
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Authors
Lorenza Bianchetti, Maurizio A. Marini, Mirko Isgrò, Alberto Bellini, Matthias Schmidt, Sabrina Mattoli,