Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761368 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠Ascorbic acid enhances norepinephrine synthesis in SH-SY5Y neuroblastoma cells. ⺠Norepinephrine synthesis increases linearly with intracellular ascorbate. ⺠Ascorbate enhances tetrahydrobiopterin-stimulated norepinephrine synthesis. ⺠Ascorbate increases protein expression of tyrosine hydroxylase. ⺠Ascorbate increases tyrosine hydroxylase expression at physiologic concentrations.
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Authors
James M. May, Zhi-chao Qu, M. Elizabeth Meredith,