Article ID Journal Published Year Pages File Type
10761376 Biochemical and Biophysical Research Communications 2012 6 Pages PDF
Abstract
► PMA regulates endogenous SERCA1 splicing in HEK293 cells. ► PMA's effects were completely abolished by the PKC inhibitor Ro 31-8220. ► PKCβII and PKCθ are the specific PKC isozymes regulating SERCA1 splicing.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Regulation of the alternative splicing of sarcoplasmic reticulum Ca2+-ATPase1 (SERCA1) by phorbol 12-myristate 13-acetate (PMA) via a PKC pathway
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