Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761379 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠A polypeptide, C-CPE, is a claudin-3/-4 binder. ⺠A C-CPE mutant, m19, is a claudin-1/-2/-4/-5 binder. ⺠C-CPE and m19 showed different mucosal absorption-enhancing activity. ⺠We may modify mucosal absorption-enhancing activity by modulating claudin specificity.
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Authors
Koji Matsuhisa, Masuo Kondoh, Hidehiko Suzuki, Kiyohito Yagi,