Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761397 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Adult growth hormone deficiency has a high prevalence of nonalcoholic steatohepatitis (NASH). ⺠However, the specific contribution of GH or IGF-I remains to be elucidated. ⺠Not only GH but also IGF-I prevented the development of NASH in a GH-deficient rat model. ⺠These results revealed a presence of GH-independent IGF-I action in the liver.
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Authors
Hitoshi Nishizawa, Michiko Takahashi, Hidenori Fukuoka, Genzo Iguchi, Riko Kitazawa, Yutaka Takahashi,