| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761398 | Biochemical and Biophysical Research Communications | 2012 | 7 Pages |
Abstract
⺠In this study we report that CD86 is attached to the cytoskeleton of antigen presenting cells. ⺠We identified sequence determinants of CD86 that are important for association to the cytoskeleton. ⺠Association of CD86 to the cytoskeleton is not involved in APC:T cell conjugate formation. ⺠CD86 association to the cytoskeleton is required for optimal activation of T cells.
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Authors
Tanya Girard, Mohamed El-Far, Denis Gaucher, Oreste Acuto, Geneviève Beaulé, Frédérique Michel, Walid Mourad, Rafick-Pierre Sékaly,