Article ID Journal Published Year Pages File Type
10761414 Biochemical and Biophysical Research Communications 2012 6 Pages PDF
Abstract
► DNA damage down-regulates of ΔNp63α and induces apoptosis independent of wild type p53. ► DNA damage-induced down-regulation of ΔNp63α occurs mainly at the mRNA level. ► Knockdown of ΔNp63α directly induces apoptosis and sensitizes cells to DNA damage. ► Exogenous expression of ΔNp63α confers cellular resistance to DNA damage.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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DNA damage down-regulates ΔNp63α and induces apoptosis independent of wild type p53
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