| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761465 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Eight human colorectal cell lines were evaluated for p53 and mortalin localization. ⺠Six cell lines displayed cytoplasmic sequestration of the tumor suppressor p53. ⺠Direct interaction between mortalin and p53 was shown in five cell lines. ⺠Cell lines positive for p53 sequestration yielded elevated p53 expression levels. ⺠This study yields the first evidence of cytoplasmic sequestration p53 by mortalin.
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Authors
Erin E. Gestl, S. Anne Böttger,