| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761473 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠Iron depletion induces upregulation of CTR2 transcription which can be abrogated by ablation of AFT1 or MAC1. ⺠Genetic deletion of either Aft1p or Mac1p removes CTR2 up-regulation induced by copper depletion. ⺠Exogenous Aft1p cannot upregulate CTR2 transcription in the absence of Mac1p. ⺠Exogenous Mac1p cannot up-regulate CTR2 transcription in the absence of Aft1p. ⺠Aft1p and Mac1p form a stable complex and synergistically upregulate CTR2 transcription.
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Authors
Jin Qi, Anning Han, Zemin Yang, Chenghua Li,