| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761498 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Overexpression of ATF3 inhibits adipocyte differentiation in 3T3-L1 cells. ⺠Overexpression of ATF3 represses C/EBPα expression. ⺠ATF3 directly binds to mouse C/EBPα promoter spanning from â1928 to â1907. ⺠ATF3 may play a role in hypoxia-mediated inhibition of adipocyte differentiation.
Keywords
EMSAATF/CREPPARγHIF-1αAP2ATF3Activating transcription factor 3 (ATF3)CCAAT/enhancer-binding proteinsC/EBPElectrophoretic mobility shift assaychromatin immunoprecipitationAdipocyte differentiationhypoxia inducible factor-1αHypoxiaadipocyte fatty acid binding proteinPromoterCHiPperoxisome proliferator activated receptor γ
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Authors
Min Kyung Jang, Cho Hee Kim, Je Kyung Seong, Myeong Ho Jung,