Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761532 | Biochemical and Biophysical Research Communications | 2012 | 7 Pages |
Abstract
⺠β-AR stimulation increases basal TRPC5 current while inducing Ca2+ transients. ⺠Gs cascade increase basal TRPC5 current and this effect accompanies cytosolic Ca2+. ⺠β-AR stimulation as well as Gs cascade increases surface expression level of TRPC5. ⺠Gs cascade-IP3R-mediated Ca2+ release potentiates TRPC5.
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Authors
Chansik Hong, Jinsung Kim, Jae-Pyo Jeon, Jinhong Wie, Misun Kwak, Kotdaji Ha, Hana Kim, Jongyun Myeong, Sung Young Kim, Ju-Hong Jeon, Insuk So,