Article ID Journal Published Year Pages File Type
10761568 Biochemical and Biophysical Research Communications 2012 7 Pages PDF
Abstract
► NOD macrophages were resistant to apoptotic and non-apoptotic cell death. ► Resistance to cell death was associated with an elevated expression of anti-apoptotic Bcl-XL. ► NOD macrophages were sensitized to cell death by ABT-737 that inhibits Bcl-XL function.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
A defect in cell death of macrophages is a conserved feature of nonobese diabetic mouse
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