Article ID Journal Published Year Pages File Type
10761584 Biochemical and Biophysical Research Communications 2012 6 Pages PDF
Abstract
► Tetrahydrobiopterin is an essential cofactor for hydroxylation reaction of cyclic amino acids. ► A novel method is developed to measure intact BH4 and dopamine by using LC-MS/MS. ► This method improves significantly assay performance for BH4 and dopamine in brain. ► It can be applied to many biological studies to directly determine BH4 and dopamine.
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