Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761584 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Tetrahydrobiopterin is an essential cofactor for hydroxylation reaction of cyclic amino acids. ⺠A novel method is developed to measure intact BH4 and dopamine by using LC-MS/MS. ⺠This method improves significantly assay performance for BH4 and dopamine in brain. ⺠It can be applied to many biological studies to directly determine BH4 and dopamine.
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Authors
Hak Rim Kim, Tae-Hyun Kim, Sung-Hyun Hong, Hyung-Gun Kim,