| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761592 | Biochemical and Biophysical Research Communications | 2012 | 8 Pages |
Abstract
⺠Circulating DNAs (CDs) can be used to detect genetic/epigenetic abnormalities in MDS. ⺠Epigenetic changes can be detected more sensitively when using plasma DNA than PBMNC. ⺠Mutation ratio in CDs may reflect the ratio in stem cell population in bone marrow. ⺠Using CDs can be a safer alternate strategy compared to bone marrow aspiration.
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Authors
Chisako Iriyama, Akihiro Tomita, Hideaki Hoshino, Mizuho Adachi-Shirahata, Yoko Furukawa-Hibi, Kiyofumi Yamada, Hitoshi Kiyoi, Tomoki Naoe,