| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761604 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠Mutations of the human desmin gene cause hereditary and sporadic myopathies and cardiomyopathies. ⺠Desminopathic myoblasts show higher stiffness compared to control cells. ⺠Higher cell stiffness leads mechanical stress contributes to higher vulnerability to excessive mechanical strain which may contribute to the progressive disease process.
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Authors
Navid Bonakdar, Justyna Luczak, Lena Lautscham, Maja Czonstke, Thorsten M. Koch, Astrid Mainka, Tajana Jungbauer, Wolfgang H. Goldmann, Rolf Schröder, Ben Fabry,